Program Rejuran HB Plus, also known as the “Red Box Rejuran,” is an advanced skin rejuvenation treatment developed to provide more comprehensive skin restoration. It combines purified PN (Polynucleotide) derived from salmon DNA with Hyaluronic Acid (HA) in a single formulation.
The PN helps support skin repair and regeneration, while Hyaluronic Acid enhances skin hydration and moisture retention. Together, Program Rejuran HB Plus helps improve skin hydration, radiance, and overall skin quality.
The treatment helps the skin appear smoother, plumper, and stronger while improving skin texture. It may also help shallow acne scars appear softer and make enlarged pores look more refined and tightened.
How Is Program Rejuran HB Plus Different from Previous Rejuran Formulas?
Program Rejuran HB Plus is an upgraded version of Rejuran Healer (Black Box Rejuran), developed with additional ingredients to provide more comprehensive skin rejuvenation and improved comfort during treatment.
1. Added Hyaluronic Acid for Enhanced Skin Hydration
Program Rejuran HB Plus contains Hyaluronic Acid (HA), which helps improve skin hydration and moisture retention. This allows the skin to appear more radiant, plump, and dewy compared to the previous formula.
2. Improved Skin Elasticity and Plumpness
The combination of PN (Polynucleotide) and Hyaluronic Acid helps deliver both skin regeneration and deep hydration. As a result, the skin appears smoother, firmer, more elastic, and healthier overall.
3. More Comfortable During Injection
Program Rejuran HB Plus contains Lidocaine, a local anesthetic that helps reduce discomfort and stinging sensations during injection, making the treatment more comfortable compared to earlier Rejuran formulations.
How Does Program Rejuran HB Plus Rejuvenate the Skin?
Program Rejuran HB Plus helps restore and repair the skin from within through active ingredients that support skin regeneration and hydration.
1. Skin Cell Repair with PDRN
PDRN (Polydeoxyribonucleotide), derived from salmon DNA, helps stimulate the repair of damaged skin cells and supports the regeneration of new skin cells. This helps improve skin strength, texture, and smoothness.
2. Deep Skin Hydration
Program Rejuran HB Plus contains Hyaluronic Acid, which helps retain moisture beneath the skin. This improves skin hydration, creates a dewy and radiant appearance, and helps soften fine lines caused by dryness.
3. Collagen and Elastin Stimulation
As PDRN stimulates the skin, it also supports the production of collagen and elastin, helping the skin appear firmer, more elastic, and more youthful.
4. Reduces Inflammation and Supports Faster Recovery
Program Rejuran HB Plus helps reduce skin inflammation while supporting the skin’s natural healing process. This can improve overall skin clarity and help reduce redness or the appearance of minor scars.
5. Long-Lasting Skin Improvement
With continued treatment as recommended by a physician, Program Rejuran HB Plus can help maintain smoother, healthier, plumper, and more radiant-looking skin over the long term.
What Are the Benefits of Program Rejuran HB Plus?
Program Rejuran HB Plus is a skin rejuvenation treatment designed to improve multiple skin concerns with a focus on hydration, skin repair, and overall skin quality.
Key Benefits of Program Rejuran HB Plus
Helps improve skin hydration and moisture retention, allowing the skin to appear more plump and hydrated — up to approximately 2 times more hydrated compared to the Original formula.
Helps brighten dull-looking skin, giving the complexion a healthier and more radiant appearance.
Strengthens the skin barrier by stimulating Fibroblast activity, which supports skin repair and regeneration.
Helps reduce the appearance of fine lines, making the skin look smoother and more refined.
Helps enlarged pores appear tighter and more refined.
Improves skin firmness and elasticity, helping the skin appear plumper and more youthful.
With continuous treatment as recommended by a physician, Program Rejuran HB Plus can help maintain smoother, hydrated, radiant, and healthier-looking skin over the long term.
Where Can Program Rejuran HB Plus Be Injected?
Program Rejuran HB Plus can be injected into multiple areas to improve skin quality and support skin rejuvenation on both the face and other parts of the body.
Facial Areas
Program Rejuran HB Plus can be injected across the entire face or targeted to specific areas such as the cheeks, forehead, under-eye area, and nasolabial folds. It is also commonly used in areas with acne scars or skin texture concerns that require skin restoration and rejuvenation.
Neck Area
Helps improve fine lines and dryness while enhancing skin hydration and smoothness around the neck.
Back of the Hands
Helps improve skin hydration and reduce dryness, making the skin on the hands appear smoother, plumper, and healthier.
Who Is Program Rejuran HB Plus Suitable For?
Individuals who want dewy, hydrated, plump, and healthy-looking skin.
Those looking to refine enlarged pores and improve the appearance of shallow acne scars.
Individuals with dry or dehydrated skin who want deep skin restoration from within.
Those who want to reduce fine lines and improve skin elasticity.
Individuals with rough, dry, or less elastic skin.
Those with sensitive or fragile skin who want gentle skin rejuvenation and recovery.
How Many cc of Program Rejuran HB Plus Are Needed?
The amount of Program Rejuran HB Plus used per session is not fixed and depends on the individual’s skin condition, treatment area, and desired results. The physician will evaluate and determine the appropriate dosage for each person.
Commonly Used Amounts
Cheek area or neck: approximately 2 cc per session
Full-face treatment: approximately 4 cc per session
In some cases, the total amount used per session may range from approximately 6–12 cc depending on the physician’s assessment and treatment plan.
How Often Should Program Rejuran HB Plus Be Done?
For optimal results, Program Rejuran HB Plus is commonly recommended once a month for approximately 3 consecutive months. This helps improve skin hydration, smoothness, radiance, and overall skin quality more effectively.
Results may last approximately 6–12 months depending on individual skin conditions and lifestyle factors. After completing the initial treatment course, maintenance sessions may be recommended every 6 months to help maintain long-term skin quality and hydration.
How Soon Can You See Results After Program Rejuran HB Plus?
After Program Rejuran HB Plus treatment, the skin typically begins to show visible improvement within approximately 2–4 weeks. The skin may appear more hydrated, plump, and smoother as the rejuvenation process develops.
Immediately after treatment, small bumps, needle marks, or mild redness may occur. These are normal post-injection reactions and usually improve gradually within approximately 7–14 days.
Can Program Rejuran HB Plus Help Improve Acne Scars?
Program Rejuran HB Plus may help shallow acne scars appear smoother and less noticeable. The Hyaluronic Acid (HA) in the formula helps improve skin hydration and plumpness, making the skin appear fuller and more even in texture.
In addition, PN (Polynucleotide) supports skin repair and regeneration, helping strengthen the skin and improve overall skin quality.
For acne scar concerns, Program Rejuran HB Plus is commonly recommended once a month for approximately 3 consecutive months. Maintenance sessions every 6 months may help maintain smoother, healthier, and more hydrated-looking skin.
How Many Sessions of Program Rejuran HB Plus Are Recommended?
To achieve more visible and long-lasting results, Program Rejuran HB Plus is generally recommended once a month for approximately 3 consecutive months, depending on the physician’s assessment and individual skin condition.
After completing the treatment course, maintenance sessions every 6 months may help maintain skin hydration, radiance, smoothness, and overall skin quality over time.
Does Program Rejuran HB Plus Cause Small Bumps After Injection?
After Program Rejuran HB Plus treatment, small raised bumps may appear on the skin, similar to other Rejuran treatments. This is a normal reaction after injection and is generally not harmful.
The bumps usually begin to subside within approximately 1–3 days. In individuals with thinner or more sensitive skin, the bumps may take slightly longer to disappear. In most cases, they gradually resolve on their own without treatment.
Aftercare and Precautions After Program Rejuran HB Plus
Small bumps from the injected solution may appear for approximately 1–3 days, depending on individual skin condition and product absorption.
Avoid pressing, massaging, or applying strong pressure to the treated area during the first 1–2 days to help reduce irritation and allow the product to settle properly into the skin.
Avoid makeup for at least 24 hours after treatment. Mild redness from the injection points usually fades within approximately 24–48 hours, depending on the individual.
You may wash and cleanse the face normally, but it is recommended to do so gently.
Drink plenty of water to help maintain skin hydration and support circulation.
Maintain consistent skincare and use moisturizing skincare products to help the skin recover and appear more hydrated and plump.
Why Choose Program Rejuran HB Plus at Reva Clinic?
Program Rejuran HB Plus at Reva Clinic is performed under the care of experienced physicians who personalize each treatment plan according to individual skin conditions and concerns to achieve natural-looking and safe results.
Highlights of Program Rejuran HB Plus at Reva Clinic
Skin Assessment by a Physician Before Every Treatment Session
Skin assessment by a physician before every treatment session to create a personalized treatment plan.
Use of Authentic Products and Clinical-Standard Protocols
Use of authentic products and clinical-standard protocols for safety and treatment effectiveness.
Injection Techniques Designed to Support Even Skin Rejuvenation
Injection techniques designed to support even skin rejuvenation, helping the skin appear smoother, healthier, plumper, and more radiant.
Detailed Aftercare Guidance and Follow-up Recommendations
Detailed aftercare guidance and follow-up recommendations to support optimal skin recovery and longer-lasting results.
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Program Rejuran HB Plus vs Vitaran I: Which Polynucleotide Treatment Is Right for You? (2026 Guide)
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